Four Byram Hills High School students were chosen as scholars, or semifinalists, in the renowned Regeneron Science Talent Search, recognized for their original research conducted in the school’s three-year Authentic Science Research Program.
The students, Lily Anchin, Benjamin Levy, Jonathan Manowitz, and Daniel Ndocaj, are among the top 300 scholars selected in the nation’s oldest and most prestigious science and math competition for high school seniors. The scholars won $2,000 each and Byram Hills will receive $8,000.
The scholars were chosen from the 2,162 students who entered the competition, the highest number of entrants since 1969. On Jan. 24, 40 of the 300 scholars will be named finalists, who will compete for more than $1.8 million in awards during a week-long competition in Washington, D.C., in March. The top prize is $250,000.
“Congratulations to our incredibly talented and hard-working student-scientists who are striving to make a difference in the world through scientific discovery,” said Stephanie Greenwald, director of the Byram Hills science research program. “Our students are passionate, dedicated, and resilient. They have produced exemplary work and we are extremely proud of this accomplishment.”
The Society for Science, which runs the competition, said scholars were chosen for their outstanding research, leadership skills, community involvement, commitment to academics, creativity and exceptional promise as STEM leaders.
“We are so proud of our four top scholars for this terrific achievement,” Principal Christopher Walsh said. “They have worked on their research for three years and I am so happy that their hard work and dedication are being recognized at such a high level. I want to thank all of the faculty and staff who have guided these students over the years as well as our community for supporting our Authentic Science Research Program.”
The Byram Hills scholars conducted advanced research in the areas of medicine and health, computer science, cellular and molecular biology, and material science. A closer look at their work:
Lily Anchin: Lily explored the viability of a specific treatment for a type of leukemia called T-cell acute lymphoblastic leukemia, a pediatric cancer with high rates of mortality. She explored CAR-T cell therapy, which works by targeting proteins that are found on cancer cells. Lily analyzed differences in these proteins among patients with varying clinical and sociodemographic characteristics, paving the way for future precision medicine.
Benjamin Levy: Benjamin utilized machine learning techniques to analyze how different genders disclose information about their mental health in online posts on Reddit. Overall, he found that men and women spoke about different issues related to their mental health. Specifically, men tended to disclose loneliness in objective ways; whereas women often discussed abuse emotionally. With future research, Benjamin's findings can be leveraged to create gender- and identity-aware approaches to mental health care, which may be able to enhance outcomes among those with mental health struggles.
Jon Manowitz: Current meat production practices are considered unsustainable, due to substantial water and land usage, as well as high greenhouse gas emissions. In response, lab-grown meat can be cultivated from small samples of live animal cells without sacrificing donor animals. Structured cell-based meat products like steaks rely on scaffolds for essential structural support. Recent studies demonstrated the potential for spinach to serve as a viable scaffold; however growing spinach specifically for this purpose adds to unsustainable environmental practices. As a unique alternative, Jon suggested the use of romaine lettuce and romaine hearts as potential scaffolds, offering an added environmental benefit as a large portion of this lettuce variety is discarded as waste. Jon's novel study uniquely investigated decellularized romaine lettuce as a lab-based meat scaffold to optimize the sustainability of lab-based meat production. His results were highly successful, paving the way for a potential new ecologically-sound method for growing lab-based meat.
Daniel Ndocaj: In medical research, scientists are limited in what they can see by the boundaries of the naked eye, as well as existing technology. This can manifest in failure to diagnose diseases or make essential discoveries due to unclear and dim images from microscopes and other diagnostic tools. Daniel demonstrated a method to enhance glowing dyes typically used in laboratory settings. Through the use of a nanomaterial that manipulates light, he demonstrated an alluring approach to produce much brighter images that has the potential to empower scientists, bringing them a step closer to viewing images that were once difficult or impossible to decipher. The implications of this novel setup include gene and cancer research.
When the top scholars were announced on Jan. 10, cheers let out at Byram Hills and students were overjoyed as they congratulated each other. The scholars said they felt gratified that their research was honored.
“It feels good to be recognized for the hard work I’ve done,” Jon said. “I’m grateful to be able to contribute to the preservation of our environment through sustainable technologies.”
Daniel said being a top scholar was rewarding. “I put a lot of effort into this work and this is the culmination of my effort,” he said. “It feels exciting.”
Noting that his work would aid medical researchers in detecting disease more effectively, he said, “I’m hopeful for the future of the field.”
Benjamin, whose research was aimed at improving mental health care, said: “This culminates all of my hard work over the past three years to help others. It’s extremely rewarding for me to be able to see my work be recognized to build a better future for everyone and better mental health care.”
Lily said: “I am so excited to be named a top scholar. Science research has been such an important part of my high school experience, and I am grateful to see all of my hard work pay off. I am honored to have my work recognized on this stage.”
The Science Talent Search, which dates to 1942, recognizes the nation’s most promising young scientists who are working to solve global challenges through rigorous research and discoveries. Alumni of the competition have won the Nobel Prize, Fields Medal, MacArthur Fellowships and other awards.
Four Byram Hills High School seniors have been named top scholars in the Regeneron Science Talent Search, the prestigious science and math competition. They are, from left, Jon Manowitz, Lily Anchin, Daniel Ndocaj and Benjamin Levy.